• 图片1

Methyl 4-hydroxycinnamate

  • CasNo:3943-97-3

Product Description

Cost-effective and customizable Methyl 4-hydroxycinnamate 3943-97-3 factory

  • Molecular Formula:C10H10 O3
  • Molecular Weight:178.188
  • Vapor Pressure:0.000421mmHg at 25°C 
  • Melting Point:144-145oC 
  • Boiling Point:306.6°Cat760mmHg 
  • PKA:8.82±0.13(Predicted) 
  • Flash Point:132.8°C 
  • PSA:46.53000 
  • Density:1.197g/cm3 
  • LogP:1.57840 

Methyl 4-hydroxycinnamate(Cas 3943-97-3) Usage

Definition

ChEBI: 4-coumaric acid methyl ester is a cinnamate ester that is the methyl ester of 4-coumaric acid. It has a role as a melanin synthesis inhibitor, a fungal metabolite, an anti-inflammatory agent, an antifungal agent and a plant metabolite. It is a cinnamate ester, a member of phenols and a methyl ester. It derives from a 4-coumaric acid.

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 28, p. 3662, 1980 DOI: 10.1248/cpb.28.3662

InChI:InChI=1/C10H10O3/c1-13-10(12)7-4-8-2-5-9(11)6-3-8/h2-7,11H,1H3/b7-4+

3943-97-3 Relevant articles

Mechanochemical Cycloreversion of Cyclobutane Observed at the Single Molecule Level

Pill, Michael F.,Holz, Katharina,Preu?ke, Nils,Berger, Florian,Clausen-Schaumann, Hauke,Lüning, Ulrich,Beyer, Martin K.

, p. 12034 - 12039 (2016)

Mechanochemical cycloreversion of cyclob...

Flavonoid glycosides from Rhazya orientalis

Itoh, Atsuko,Kumashiro, Tomoko,Tanahashi, Takao,Nagakura, Naotaka,Nishi, Toyoyuki

, p. 352 - 357 (2002)

Six new flavonoid glycosides; quercetin ...

Conjugation with dihydrolipoic acid imparts caffeic acid ester potent inhibitory effect on dopa oxidase activity of human tyrosinase

Micillo, Raffaella,Sirés-Campos, Julia,García-Borrón, José Carlos,Panzella, Lucia,Napolitano, Alessandra,Olivares, Conchi

, (2018)

Caffeic acid derivatives represent promi...

A drug delivery system based on switchable photo-controlled p-coumaric acid derivatives anchored on mesoporous silica

Beňová, Eva,Zeleňák, Vladimír,Halamová, Dá?a,Almá?i, Miroslav,Petrul'ová, Veronika,Psotka, Miroslav,Zeleňáková, Adriána,Ba?kor, Martin,Hornebecq, Virginie

, p. 817 - 825 (2017)

A stimuli-responsive drug delivery syste...

Ultrafast dynamics of isolated model photoactive yellow protein chromophores: "Chemical perturbation theory" in the laboratory

Vengris, Mikas,Larsen, Delmar S.,Van Der Horst, Michael A.,Larsen, Olaf F. A.,Hellingwerf, Klaas J.,Van Grondelle, Rienk

, p. 4197 - 4208 (2005)

Pump-probe and pump-dump probe experimen...

Photoinduced Regioselective Olefination of Arenes at Proximal and Distal Sites

Ali, Wajid,Anjana, S. S.,Bhattacharya, Trisha,Chandrashekar, Hediyala B.,Goswami, Nupur,Guin, Srimanta,Maiti, Debabrata,Panda, Sanjib,Prakash, Gaurav,Saha, Argha,Sasmal, Sheuli,Sinha, Soumya Kumar

supporting information, p. 1929 - 1940 (2022/02/01)

The Fujiwara-Moritani reaction has had a...

TRPV3 inhibitor and preparation method thereof

-

Paragraph 0240; 0241; 0242; 0243; 0244; 0245; 0246, (2021/04/10)

The invention discloses a TRPV3 inhibito...

Prenylated trans-cinnamic esters and ethers against clinical fusarium spp.: Repositioning of natural compounds in antimicrobial discovery

Balmas, Virgilio,Carta, Paola,Casalini, Stefano,Chtioui, Wiem,Delogu, Giovanna,Dettori, Maria A.,Fabbri, Davide,Migheli, Quirico,Oufensou, Safa

, (2021/06/14)

Onychomycosis is a common nail infection...

Dirigent Proteins Guide Asymmetric Heterocoupling for the Synthesis of Complex Natural Product Analogues

Kim, Stacie S.,Sattely, Elizabeth S.

supporting information, p. 5011 - 5021 (2021/05/04)

Phenylpropanoids are a class of abundant...

3943-97-3 Process route

regaloside B

regaloside B

methyl 4-hydroxycinnamate
3943-97-3

methyl 4-hydroxycinnamate

2-O-β-D-glucosyl-glycerol
534-68-9,3879-81-0,5768-72-9,6245-27-8,10588-30-4,22160-26-5,40593-14-4,128163-38-2,5624-47-5

2-O-β-D-glucosyl-glycerol

Conditions
Conditions Yield
With sodium methylate; In methanol; for 2h; Yield given; Ambient temperature;
methanol
67-56-1

methanol

osmanthuside B
97549-57-0,94492-23-6

osmanthuside B

p-hydroxyphenethyl alcohol
501-94-0

p-hydroxyphenethyl alcohol

methyl 4-hydroxycinnamate
3943-97-3

methyl 4-hydroxycinnamate

Conditions
Conditions Yield
With acetyl chloride; for 0.5h; Heating;

3943-97-3 Upstream products

  • 67-56-1
    67-56-1

    methanol

  • 7400-08-0
    7400-08-0

    p-Coumaric Acid

  • 52820-26-5
    52820-26-5

    4-hydroxyphenylacryloyl chloride

  • 110-16-7
    110-16-7

    maleic acid

3943-97-3 Downstream products

  • 6049-54-3
    6049-54-3

    3-amino-3-(4-hydroxyphenyl)propionic acid

  • 59576-98-6
    59576-98-6

    (E)-p-coumaric amide

  • 70193-44-1
    70193-44-1

    (E)-3-{4-[3-(4-Chloro-phenoxy)-2-oxo-propoxy]-phenyl}-acrylic acid methyl ester

  • 60377-05-1
    60377-05-1

    3-<4'-(2-Methoxycarbonylvinyl)-phenoxy>-1-(4'-chlorphenoxy)-propanol-(2)

*Product Name
CAS
Purity
Quantity
Company name
*Email
*Other Description
*Code
Fields with*are required
Submit